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Bright field mode was used to detect for the development of blue color under a Zeiss Axioscope microscope equipped with a Zeiss HRC microscope camera (200 total magnification)

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The delivery of siRNA by nanoparticles has been examined on genes associated with immune response, lipid metabolism and genes coding receptors expressed on myeloid cells 2 (TREM2) and apolipoprotein E (APOE) (103, 104)

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