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The CREDENCE clinical trial evaluated the effects of canagliflozin 100 mg daily versus placebo in 4401 patients with T2DM and chronic kidney disease (CKD)
It is associated with pathways that influence: Inflammatory signaling Blood vessel communication Neuroimmune interactions VIP is often discussed in regenerative medicine for its relationship with inflammation balance and circulation
Behavioral effects: Some patients experience reduced cravings for alcohol, smoking, or even compulsive shopping
doi: 10.1113/jphysiol.2010.201343
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