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Furthermore, an evaluation of the risk equations of models for CV risk (including Framingham and SCORE) has reported that these models do not provide reliable estimates of CV risk in patients with T2D [50]

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Table 15: Analysis of the Composite 3 point MACE and Individual Cardiovascular Endpoints in DEVOTE Figure 3: Cumulative Event Probability for Time to First MACE in DEVOTE Hypoglycemia Outcomes Patients with T2DM and Atherosclerotic CVD The pre-specified secondary endpoints of event and incidence rates of severe hypoglycemia were sequentially tested

My metabolism is as slow as a snails, but I actually lost 29 Ibs in a month

At the 12mg dose, the average increase was around 2.66.7 beats per minute compared to baseline, peaking at approximately 24 weeks