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Bottom line GLP-1 drugs can be effective tools for weight loss and blood sugar control
Animal studies hint at risks like birth defects and pregnancy loss
Fatigue that appeared manageable early on can become more pronounced if nutritional deficiencies have developed due to prolonged reduced food intake
Importantly, multivariate models with many covariates risk overfitting and unreliable parameter estimates, particularly in analyses with a low number of outcome events [41]
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