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Prostaglandin E1: A review[J]

Eur J Pharm Biopharm

Moreover, that hypothesis (James et al., 1999) has been revised and implemented over the years, leading researchers to hypothesize that maternal polymorphisms of genes involved in folate metabolism could not only favor chromosome 21 malsegregation but, when transmitted to a DS embryo, could also account for the probability that it will survive up to the birth (Martnez-Fras et al., 2006), or contribute to the onset of congenital defects (Brandalize et al., 2009

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