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Semaglutide has the longest safety record, with data now extending beyond five years in the cardiovascular outcomes trials

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Ongoing Research and Development GLP-1R agonists have demonstrated significant cardiovascular benefits in addition to effectively lowering blood glucose levels, including major cardiovascular events risk reduction

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New studies suggest that that GLP-1 medications may be linked to a 30% higher risk of developing osteoporosis, especially in people with Type 2 diabetes