Consistent with this expectation, Argyrakopoulou et al reported that in a cohort of obese individuals treated with liraglutide, the dominant change was a reduction in fat mass, accompanied by only a minimal decline in lean mass
Weekly Injection Format Retatrutide is administered as a once-weekly injection during trials
So you always have to worry about that when you're doing an observational study
The most common adverse reactions were nausea, diarrhea, constipation, and vomiting, and the treatment discontinuation rate due to adverse reactions was 11.3% in the 12mg group and 6.9% in the 9mg group, which was higher than the placebo group (4.9%)
Gastrointestinal Reactions: Various mild gastrointestinal complaints have been reported during the long-term administration of oral L- or D,L-carnitine