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Serious but Rare Risks GLP-1 medications can aggravate or trigger severe pancreatic inflammation in some patients. Both oral and injectable GLP-1 medications may cause gallbladder disease, and in rare cases involving patients with relevant risk factors, there have been associations with thyroid changes observed in animal studies. A serious allergic reaction is possible but uncommon

PMCID: PMC7830011

For metabolites, a nominal P 0.05 and FDR 0.05 was considered significant, and a P 0.05 and FDR 0.15 considered marginally significant

878 Other active substances in Chinese medicine, such as ruscogenin, curcumin, baicalein, brevilin A, icariin, and cardamonin could also inhibit chondrocyte ferroptosis, reduce cartilage destruction in osteoarthritis

Participants eating traditional sized meals (500 to 700 calories) experienced nausea rates of 41%