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The most prevalent and consistent dose-limiting side effects observed across studies of FGF21 analogs in patients with metabolic disease are gastrointestinal (GI), including mild-to-moderate nausea and diarrhea (183, 245, 246, 298, 301)

Spending money on high-dose B12 pills for this purpose is unlikely to be beneficial and should not replace evidence-based weight management approaches

Levels naturally decline with age, chronic stress, poor sleep, alcohol use and sustained high-training loads