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Recent preclinical studies have demonstrated the potential of CRISPR-Cas9 genome editing to address key mutations underlying HCM, such as missense mutations in the MYH7 gene 318,319 and premature stop codon mutations in the MYBPC3 gene
HR = hazard ratio
Do not use mouth-drying agents like alcohol-based mouthwash
Khng thuc gn ni tr em chi a, trnh trng hp tr em c th nghch v v tnh ung phi
A more in-depth discussion of the effects of desolvation will be given in Chapter 6, discussing enzyme reaction mechanisms
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