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GLUD1 mutations reduce the sensitivity of the enzyme to its inhibitor GTP, which fuels hyperinsulinaemia/hyperammonaemia (HI/HA) syndrome, a condition characterized by elevated blood NH4 + levels and low glucose levels (De Lonlay et al., 2001
About this article Cite this article Bono, S., Feligioni, M
Glutathione IV remains in the bloodstream for 2 to 4 hours , depending on metabolism and hydration
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Research priorities for the coming years include optimizing dosing regimens, developing tissue-specific delivery methods, and identifying biomarkers that can predict treatment response
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