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Cardiovascular Outcomes Trial of Semaglutide in Patients with Type 2 Diabetes Mellitus SUSTAIN 6 (NCT01720446) was a 104-week, double-blind trial in which 3,297 patients with type 2 diabetes and high risk of cardiovascular events were randomized to semaglutide 0.5 mg once weekly, semaglutide 1 mg once weekly, or placebo in addition to standard-of-care
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GLP-1 GLP-1 is secreted by the pancreas and by intestinal L-cells in response to glucose-induced insulin release (177, 178)
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