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Both of these conditions can cause referred pain in the upper abdomen or back

Sleep deprivation increases ghrelin (the hunger hormone), reduces leptin (the satiety hormone), increases insulin resistance, and promotes cortisol-driven visceral fat storage

Am J Chin Med 41(03):503513 Boccardi V, Tinarelli C, Mecocci P (2017) Nutraceuticals and cognitive dysfunction: focus on Alzheimers disease