These medications are relatively new
You more than likely already know the names: semaglutide (Ozempic, Wegovy) and the dual GIP/GLP-1 agonist tirzepatide (Mounjaro, Zepbound)
The most well-known examples, apart from pioglitazone, are fenofibrate, pemafibrate, seladelpar, elafibranor and lanifibranor, which have been studied in various trials regarding their effect on liver inflammation and fibrosis, without particular success, with the exception of lanifibranor, a pan-PPAR agonist, which was shown in a phase 2b RCT (NATIVE-NCT03008070) to improve ballooning and inflammation, without worsening of fibrosis
You should contact your GP or NHS 111 if you experience severe, persistent vomiting or diarrhoea that prevents you from keeping down fluids, as this can lead to dehydration and electrolyte imbalance
Studies have shown that antidiabetic drugs such as pioglitazone significantly reduce the enzyme activity of skeletal muscle TNF- and TACE and improve the mitochondrial proteomic profile of skeletal muscle in subjects with T2D [68]