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Appropriate patient selection, informed consent, comprehensive monitoring, and adherence to all regulatory requirements remain the responsibility of the prescribing clinician.

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Mancini GBJ, OMeara E, Zieroth S, Bernier M, Cheng AYY, Cherney DZI, et al

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The clinical studies on melatonin show varied results

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Drug-Induced Pigmentation: Medicines can sometimes cause darkening of the lips and surrounding skin

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Knopp et al., 1999

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