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Ipamorelin is a synthetic pentapeptide belonging to the growth hormone secretagogue (GHS) class
This biological hunger can hit all at once, leading to a restart of the binge cycle even when on medication , or can come back with a vengeance when finishing weight loss medication , if binge eating patterns have not been addressed separately
Across several GLP-1 trials, roughly 25-40% of the total weight lost has come from lean tissue
However, if you are high risk for heart disease, have had a heart event or the equivalent (stroke, stent), or do not require 15-20% weight loss, semaglutide / Wegovy may be a better choice
So always start slowly, look at the dosage, increase gradually
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