They often result from a combination of genetic, environmental, and lifestyle factors, and share common pathological mechanisms, such as chronic oxidative stress, excitotoxicity, neuroinflammation, and mitochondrial dysfunction
SGLT2 inhibitors, DPP-4 inhibitors, ERR agonism, SIRT activation, BCAA catabolic modulation, and mitochondrial stabilizers are all represented in recent experimental or translational literature (45, 49, 59, 64)
One reported effect of milk thistle is that it can boost breast milk production in lactating mothers
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Q.et al (2023)