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In obese mice, chronic treatment with AOD-9604 increased fat oxidation and reduced weight gain, without the adverse effect on insulin sensitivity seen with intact growth hormone

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Others might theoretically conflict with metabolic pathways already being modulated

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Furthermore, research published in the journal Obesity Science & Practice highlighted the benefits of semaglutide for long-term weight maintenance, demonstrating sustained reductions in body weight and improvements in obesity-related comorbidities over time