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Alternative options like Rybelsus or Wegovy (injectable or oral) are also worth discussing with your provider

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And, Secher added, since c-Fos is not a global marker, it is possible that many other brain regions were also indirectly activated by semaglutide but did not show up with the c-Fos signal

The most reasonable choice depends on the clinical objective, formulation quality, route, tolerance, convenience and evidence proportional to the claim being made