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Gallbladder disease : Tirzepatide is associated with increased risk of gallbladder disease, including cholelithiasis and cholecystitis
It is commonly used in both performance and rehabilitation contexts
Another cause for concern is the risk of complications under anesthesia
1 The discovery, description, and clinical development of GLP-1 medications spans 30 years with contributions from multiple investigators
When You Should Use the Longer (3-Month or More) Timeline Stick with the conservative 3-month approach if youre under 35 and have time to be conservative, youve had extended GLP-1 use (on medication for 6+ months), your baseline cycles were irregular before starting medication (especially with PCOS), youve had significant weight loss (50+ pounds) and need more time for metabolic stabilization, you need time to transition to pregnancy-safe diabetes medications and optimize glucose control, or you have a history of miscarriage and want to optimize conditions
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