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Consequently, glial cells are currently categorized using diverse terminology and classified into numerous subtypes to reflect their biological heterogeneity in response to various stress (Hartenstein and Giangrande, 2018)

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Researchers studying receptor desensitization also use paired GHRH/GHS protocols to compare downregulation kinetics against single-agent controls, since repeated stimulation of the GHRH receptor alone can blunt responsiveness over time in ways that combined signaling may partially offset