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Across preclinical studies, Epitalon has shown: Telomerase activation and telomere extension: Via TRAP assays and fibroblast lifespan extension beyond the Hayflick limit Epigenetic remodeling: Reversal of chromatin aging, histone modulation, and gene promoter binding Redox homeostasis: Increased antioxidant enzymes (SOD, NQO1, catalase) and reduced ROS, lipid peroxidation, and DNA damage Circadian restoration: Upregulation of AANAT/pCREB, normalized melatonin and cortisol rhythms, and clock gene modulation in humans Cancer risk reduction: Reduced tumor multiplicity and delayed onset in HER-2/neu and colon cancer models
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doi:10.1016/j.bcp.2019.02.008 Dimet-Wiley A, Latham CM, Brightwell CR, et al
Skiing accidents in Whistler, hockey collisions in Toronto rinks, cycling mishaps on the Bow River pathway, or simple falls on icy Edmonton sidewalks all lead to the same frustrating prognosis: wait it out
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