Chang J, Leong RW, Wasinger VC, Ip M, Yang M, Phan TG ~ J Med Food
Thats because weight change is often roughly proportional to starting weight
Efficacy analyses were performed on two sets: the full analysis set, defined as all unique randomized patients grouped according to the treatment assigned at randomization, thereby following the intent-to-treat principle, and an on-treatment analysis, defined as all exposed patients while they were receiving treatment (that is, had received at least one dose in the previous 35 d), grouped according to the treatment that they received
Month 3
If weight loss plateaus or is less than expected after 3-4 months at the maintenance dose, clinicians should reassess adherence, evaluate for medication interactions, and reinforce lifestyle modifications