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The cited half-life range comes from pharmacokinetic studies in animal models and is consistent with the general behavior of unmodified small peptides in blood
It hits gene expression controls, including potential histone protein binding and regulation of specific DNA regions
Primary cultures of satellite cells were prepared from the upper hindlimb and back muscles of 910 month-old male rats and cultured for 24 h beginning at 24-h post-plating in DMEM-10% HS containing 5 ng/ml HGF that was pre-treated with GSSSG and LASSS separately at 1:4000 molar ratio just prior to peroxynitrite treatment (1:2000 to HGF
HPLC purity should be above 98%
Acknowledgements This work was funded by the DFG grant DE 1431/20-1 to M.D
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