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The cells are suitable for use in high-throughput systems to screen for inhibitors or agonists

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However, once approved, physicians can legally prescribe drugs for off-label uses, as seen with Ozempic and other GLP-1 receptor agonists for weight loss

Semaglutide binds to the GLP-1 receptor with high affinity, stimulating glucose-dependent insulin secretion, suppressing inappropriately elevated glucagon, delaying gastric emptying, and reducing appetite through central and peripheral mechanisms [29]