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doi: 10.3389/fphar.2021.698905 291 WangS.ShengY.TuJ.ZhangL

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Based on the evidence that NOX4 is highly expressed in uterine fibroid tissues [Citation47], it can be inferred that progesterone can provide auxiliary support for E-induced NOX4 activity in fibroid cells through a similar mechanism, thereby potentially synergistically amplifying the pro-oxidative effect of E functionally

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