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Reported side effects Mild headache or fatigue typically transient during initial use Mild gastrointestinal discomfort reported in some oral formulation users Sleep disruption or irritability potential sign of overstimulation Theoretical safety concerns Critical note: Because Dihexa activates the HGF/c-Met pathway which promotes cellular growth and repair there is a theoretical concern that it could potentially stimulate unwanted cell proliferation in individuals with active cancer or high cancer risk

Effect of long-term vagal stimulation on food intake and body weight during diet induced obesity in rats

P = 0.04) (Supplemental Table 3)

Cilette believes that Ozempic is the culprit

Int Immunopharmacol 71:233240