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Description

10.1111/obr.12488 Obes Rev

Polyphenolscompounds found in berries, green tea, dark chocolate, and red wineenhance the function of existing GLP-1 receptors and improve gut-barrier integrity

The article points to receptor location

In the multiple-ascending-dose arm at steady state (Day 28), the mean half-life increased to 48.1 to 67.5 hours across doses, reflecting the accumulation kinetics of a compound with nonlinear pharmacokinetics

MW: Writing review and editing, Conceptualization