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If you're tired after B12 shot or experiencing worsening symptoms, there are several steps you can take to mitigate these effects and optimize the benefits of B12 supplementation

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For instance, you may want to add extra saline for increased hydration or B Complex for vitamin support

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With respect to body weight, a higher baseline body-mass-index is a predictor of absolute weight reduction, albeit with substantial body weight loss even in those with a BMI 50 years with either chronic kidney disease and an eGFR of less than 60 ml/min per 1.73 m 2 or history of congestive heart failure (NY Heart Association Class II or III)