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Tirzepatide is appropriate for medically-supervised weight loss in adults with BMI 30 or 27 with obesity-related comorbidities

Other autoimmune conditions can also have this effect

That logic works for something like fentanyl, where decades of data tell us exactly how dangerous the status quo is test strips and safer supply reduce a known, measured risk

The overexpression of SLC7A11, a cystine/glutamate antiporter SLC7A11 (also known as xCT), is involved in the suppression of ferroptosis

However, concerns regarding the safety of such agents, in particular the increased risk of diabetic ketoacidosis (DKA) with SGLT2is, have restricted their widespread adoption in type 1 diabetes [15]