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Its about recognizing that profound change and gentle support are two sides of the same coin
Gastrointestinal events were the most common adverse effect, dose-related and mostly mild to moderate, eased by starting low
The Beers Criteria, a guideline for medication use in older adults, lists NSAIDs as potentially inappropriate due to high risk of GI bleeds and renal failure
As a result, altered intracellular glutathione homeostasis has been widely used as an indicator of oxidative stress
These changes often precede and exacerbate ALS symptoms
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