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Furthermore, reduction in bioavailable NO induces pathogenic vascular smooth muscle cell proliferation in vitro and vasoconstriction in vivo due to suppression of cGMP kinase signaling 40,41
Experimental Biology and Medicine 77, 418420 (1951)
Gastric emptying is a complex physiologic process controlled by the physical and chemical composition, sympathetic and parasympathetic innervations of the stomach, and circulating neuro-endocrine transmitters
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Through systematic analysis of clinical trials, meta-analyses, and emerging evidence from landmark studies like SELECT, this paper evaluates whether GLP-1 agonists represent a transformative breakthrough or an overhyped intervention with significant limitations
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