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Curcumin's Effect on Drug Metabolism Curcumin inhibits CYP3A4, CYP1A2, CYP2D6, and UGT enzymes in vitro [6]
These changes were statistically significant, and the direction of effect suggests possible neuroprotection, but the magnitude was very small (particularly if we compare these results to those in the Phase 3 trials of AD drugs that are now approved, such as lecanemab or donanemab) , the sample limited, and there is no evidence these shifts translate into meaningful clinical benefit
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BPC-157 was added to the WADA Prohibited List in 2022 under S0: Non-Approved Substances
Metabolites 11(2):73 Seghieri M, Rebelos E, Gastaldelli A et al (2013) Direct effect of GLP-1 infusion on endogenous glucose production in humans
