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doi: 10.1002/hep.26717 120 ArmstrongMJHoulihanDDRoweIAClausenWHElbrndBGoughSCet al

To assess whether the anti-obesity properties of GLP-1MK-801 are dependent on this key energy balance-governing pathway, we tested the weight loss efficacy in DIO Mc4r -KO (also known as melanocortin-4 receptor) mice

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Benefits for SGLT-2 inhibitors and GLP-1 receptor agonists on the absolute scale were largest for those with heart failure, chronic kidney disease, or those using mineralocorticoid receptor antagonists

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