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In summary, nanotechnology demonstrates multi-dimensional mechanistic advantages in regulating microcirculatory disorders associated with RIRI, including vasomotor regulation, anti-thrombotic effects, and endothelial barrier protection
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Further, the increase in mtROS production correlated with a decline in the expression and activity of the mitochondrial antioxidant enzyme Mn +2 superoxide dismutase (MnSOD), and a decline in the cytosolic glutathione peroxidase (GPx) activity and GSH content in the myocardium of chronically infected animals (Wen and Garg, 2004) and in ChD patients (Prez-Fuentes et al., 2003
McFadyenJDKieferJBraigDLoseff-SilverJPotempaLAEisenhardtSUet alDissociation of C-reactive protein localizes and amplifies inflammation: evidence for a direct biological role of C-reactive protein and its conformational changes
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