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The potential molecular mechanisms underlying these effects included disturbances in redox homeostasis (as evidence by the enhanced production of ROS and reactive nitrogen species), failure of enzymatic and nonenzymatic cytoprotective mechanisms involving the glutathione system as well as nuclear factor kappa B (NF-B) and fibroblast growth factor 2-mediated pathways, and impaired mitochondrial function
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10.1016/j.cell.2006.01.016 60 XiaoT.RoeserT.StaubW.BaierH
Thus, it is not surprising that a high concentration of L-carnitine is found in cardiac muscle and that L-carnitine is considered to be vital for the proper mechanical functioning of the heart
It can be taken with or without food as directed by your doctor
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