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The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

Of the study group, 76% had never used an obesity medication before semaglutide and 24% previously used another obesity medication

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Ozempic, Rybelsus) and chronic weight management (Wegovy) at different doses

these are the lowest values from cardiovascular outcomes trials of the more common SGLT2is and GLP-1 RAs used in Australia [41, 42]