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3.5 GHK-Cu regulated the SIRT1/STAT3 pathway SIRT1, which is closely associated with cellular metabolism and stress responses, also interacts with the STAT3 pathway (Figures 6AD, DSS-induced mice exhibited significantly increased SIRT1 expression and decreased p-STAT3 expression compared to the Control group
These emerging applications offer researchers opportunities to study senescence contributions to neurodegeneration and develop novel approaches for studying brain aging and neurodegenerative disease mechanisms
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