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Body weight and BMI play a role in determining eligibility for weight management trials, with most retatrutide studies enrolling adults with a BMI of 30 kg/m or above, or 27 kg/m or above in the presence of weight-related comorbidities such as hypertension or dyslipidaemia
PMID 13056638
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PubMed Central, Schaubschlger, W
Tirzepatide also improves renal hemodynamics by promoting natriuresis and vasodilation, which lowers intraglomerular pressure and preserves the integrity of the glomerular filtration barrier (Urva et al
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