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Thus, the reduced levels of both glutamate and pyroglutamate observed in barren habitat sea urchins from this study likely reflects their use as energy substrates, coinciding with an increased need for NADH production from alternative sources under conditions of nutrient scarcity

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Studies reveal enhanced fatty acid oxidation, increased energy expenditure, and improved metabolic efficiency through direct NNMT inhibition, positioning it as breakthrough tool for investigating obesity mechanisms without appetite suppression