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It acts as a copper carrier and has been shown in cell and animal studies to upregulate collagen and glycosaminoglycan synthesis, modulate inflammation, and influence gene expression across hundreds of pathways

doi:10.5858/2003-127-1603-momlic

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The nuclear form of glutathione peroxidase 4 is associated with sperm nuclear matrix and is required for proper paternal chromatin decondensation at fertilization

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(/) knockout mouse