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[10] Tertomotide Doti N, Mardirossian M, Sandomenico A, Ruvo M, Caporale A (August 2021)

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Some patients may experience anxiety symptoms during semaglutide treatment due to reduced calorie intake, disrupted sleep, dehydration, or rapid lifestyle adjustment

In normal conditions, leptin prevents body weight gain by suppressing feeding (144, 145) and increasing energy expenditure (146148)