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Ethics declarations Ethics approval and consent to participate The Ethical Committee of Hospital Universitario Puerta del Mar (Cdiz, Spain) approved the study protocol (Ref

The review appears in the journal According to the Centers for Disease Control and Prevention (CDC), just over 40% of adults in the United States have obesity, which is defined as having a body mass index (BMI) of 30 or higher

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Impaired activity of methionine synthase results in elevated blood concentrations of homocysteine, while impaired activity of L-methylmalonyl-CoA mutase results in increased concentrations of a metabolite of methylmalonyl-CoA called methylmalonic acid (MMA) in blood and urine