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These effects typically emerge during dose escalation and often diminish over several weeks as physiologic adaptation occurs
The mechanism leading to 5-oxoprolinuria is the following: decreased activity of 5-oxoprolinase leads to decreased conversion of 5-oxoproline to glutamate
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Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse
Rather than identifying definitive diagnostic biomarkers, this study highlights a small number of metabolitesmost notably leucine, betaine, and coumarinthat may contribute to metabolic stratification of ASD in future work
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