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It is important to look at the context of this warning: Animal Studies: The warning is based on studies in rats and mice, where long-term exposure to these drugs led to the development of medullary thyroid carcinoma (MTC)

Research shows that combining higher protein intake with resistance exercise preserves lean mass and improves body composition during caloric deficit, and a 2025 systematic review found that exercise interventions alongside GLP-1 medications produced better outcomes for body composition than medication alone

Additionally, NR treatment led to an improvement in the cognitive functions of mice 242,243

Robison says

(4) Similarly, the clinical study on models of diabetic neuropathic ulcers reported that GHK-Cu, combined with standard wound care, appeared more impactful for wound closure than standard care alone