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The ones waiting for the trend to become undeniable are ceding that window, and Circanas analysis adds a further layer of urgency: the categories with the steepest GLP-1 spending declines are often the same categories with the most bloated SKU counts, the result of years of incremental product extensions that made sense when volume was growing but become expensive to maintain as demand contracts
Side effects are generally mild, but higher doses may cause diarrhoea, heartburn, stomach pain, vomiting, and headache
With an estimated one in eight adults now taking a GLP-1, experts fear that vulnerable patients might start misusing the drugs to achieve weight loss at any cost
Obesity-driven growth of E0771 tumors was blunted by both tirzepatide and CCR ( Supplementary Figure 2D )
