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Professor of Medicine, Head of Diabetes Centre, Institute for Clinical and Experimental Medicine

If those levels drop too quickly, the period of metabolic adjustment can make cells vulnerable to injury. But a rapid drop in blood sugar likely isnt the mechanism associated with NAION, since most cases of blindness happen many months after starting the medication

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Elsewhere Nicolae Paulescu, a Romanian physiologist took advantage of enforced retirement in 1916 when German troops occupied Bucharest to develop an aqueous pancreatic extract which proved effective at lowering blood and urine sugar levels in dogs that previously had their pancreata removed

Moreover, the potential side effects of antioxidants may limit their therapeutic value