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Pagets disease of bone, which causes abnormal bone growth, can alter spaces in the spinal canal

Figure 1 illustrates how aging is associated with progressive changes in circadian rhythm amplitude, phase timing, and sleep architecture

This is not inherently problematic for a new product, but it means we are working with preliminary evidence rather than established clinical proof

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To test this, we synthesized and characterized the GO@GSH-FA nanocomposite, evaluated its neuroprotective effects in OGD/R cell models, and assessed its therapeutic efficacy in Endothelin-1 (ET-1) induced cortical ischemia models