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This can create inequality in access

Key secondary endpoints included non-inferiority of tirzepatide (5 mg) compared to insulin degludec in HbA1c reduction, superiority of all tirzepatide doses over insulin degludec in HbA1c reduction and weight loss, and the proportion of participants achieving an HbA1c level below 7.0% at week 52

Only the combination delivered all three together: HbA1c reduction, insulin sensitivity improvement, and cardiorespiratory fitness gains

10.1038/clpt.1981.154 63 NauckM

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