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Patient Counseling Patients should be told to inform their surgical, anesthesia, dental, endoscopy, and procedural teams if they use GLP-1 or dual incretin medications

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When to Consider Switching to a Dual-Compound or Alternative GLP-1 Therapy If plateau strategies don't produce results within 6 to 8 weeks, or if you've already optimized your dose with your provider, switching to a different compound may be beneficial

The figure shows the mean percent change in body weight during the entire trial, comparing the continued use of semaglutide versus a placebo (week 0-68)